A comprehensive review of the multifaceted role of cannabinoid receptor type 2 in neurodegenerative and neuropsychiatric disorders
Leer MasChanges in neurobiological markers of reactivity to alcohol-related stimuli in alcohol-dependent patients after two years of treatment
Leer MasCannabinoid Analgesia in Postoperative Pain Management: From Molecular Mechanisms to Clinical Reality
Leer MasAging Deteriorates Blood Brain Barrier Function and Polarizes Adaptive T Cell Expansion Contributing to Neurocognitive Damage in Experimental Cirrhosis
Leer MasAdolescent intermittent ethanol exposure decreases perineuronal nets in the hippocampus in a sex dependent manner: Modulation through pharmacological inhibition of RPTPβ/ζ
Leer MasAdditive antinociceptive action of intrathecal anandamide reuptake inhibitor and morphine in the management of post-incisional pain in rats
Leer MasFetal Cannabinoid Syndrome: Behavioral and Brain Alterations of the Offspring Exposed to Dronabinol during Gestation and Lactation
Leer MasIsobolographic Analysis of the Cytoprotective Effect of Dapsone and Cannabidiol Alone or Combination upon Oxygen–Glucose Deprivation/Reoxygenation Model in SH-SY5Y Cells
Leer MasMethods to Identify Cognitive Alterations from Animals to Humans: A Translational Approach
Leer MasRegulation of Cortico-Thalamic JNK1/2 and ERK1/2 MAPKs and Apoptosis-Related Signaling Pathways in PDYN Gene-Deficient Mice Following Acute and Chronic Mild Stress
Leer MasCannabidiol regulates behavioral and brain alterations induced by spontaneous alcohol withdrawal
Leer MasDiferences in Substance Use Disorders and Other Mental Disorders in Mental Health and Addiction Settings: Sociodemographic, Clinical, Drug Treatment, and Gender Diferences
Leer MasEmotional Processing and Maltreatment During Childhood as Factors of Vulnerability to Alcohol Abuse in Young Adults
Leer MasAlterations of BDNF, mGluR5, Homer1a, p11 and excitatory/inhibitory balance in corticolimbic brain regions of suicide decedents
Leer MasSex differences in the comorbidity of patients seeking a first treatment for Alcohol Use Disorder
Leer MasAssociations of hypomagnesemia in patients seeking a first treatment of alcohol use disorder
Leer MasRole of CB2 cannabinoid receptor in the development of food addiction in male mice
Leer MasCannabidiol repairs behavioral and brain disturbances in a model of fetal alcohol spectrum disorder
Leer MasEditorial: Cannabidiol treatment in neurotherapeutic interventions, volume II
Leer MasUnveiling behavioral and molecular neuroadaptations related to the antidepressant action of cannabidiol in the unpredictable chronic mild stress model
Leer MasCBD-mediated regulation of heroin withdrawal-induced behavioural and molecular changes in mice
Leer MasCannabinoid CB1 Receptor Involvement in the Actions of CBD on Anxiety and Coping Behaviors in Mice
Leer MasImmunomodulatory Role of CB2 Receptors in Emotional and Cognitive Disorders
Leer MasPharmacological strategies for post-traumatic stress disorder (PTSD): From animal to clinical studies
Leer MasMolecular Alterations of the Endocannabinoid System in Psychiatric Disorders
Leer MasCannabidiol attenuates hypersensitivity and oxidative stress after traumatic spinal cord injury in rats
Leer MasDifferences in Substance Use Disorders and Other Mental Disorders in Mental Health and Addiction Settings: Sociodemographic, Clinical, Drug Treatment, and Gender Differences
Leer MasRole of Cannabinoid CB2 Receptor in Alcohol Use Disorders: From Animal to Human Studies
Leer MasDifferences in Gene Expression of Endogenous Opioid Peptide Precursor, Cannabinoid 1 and 2 Receptors and Interleukin Beta in Peripheral Blood Mononuclear Cells of Patients With Refractory Failed Back Surgery Syndrome Treated With Spinal Cord Stimulation: Markers of Therapeutic Outcomes?
Leer MasCannabidiol and sertraline regulate behavioural and brain gene expression alterations in an animal model of PTSD
Leer MasCannabidiol prevents the reinstatement of cocaine-induced conditioned place preference in mice
Leer MasTherapeutic potential of the cannabinoid CB2 receptor in neuropsychiatry
Leer MasThe administration of sertraline plus naltrexone reduces ethanol consumption and motivation in a long-lasting animal model of post-traumatic stress disorder
Leer MasCannabidiol Modulates Behavioural and Gene Expression Alterations Induced by Spontaneous Cocaine Withdrawal
Leer MasPairing binge drinking and a high fat diet in adolescence modulates the inflammatory effects of subsequent alcohol consumption in mice
Leer MasRole of Cannabidiol in the Therapeutic Intervention for Substance Use Disorders
Leer MasCannabis use in pregnant and breastfeeding women: behavioral and neurobiological consequences.
Leer MasBiomarkers in Psychiatry: Concept, Definition, Types and Relevance to the Clinical Reality
Leer MasAssociation of cannabinoid receptor genes (CNR1 and CNR2) polymorphisms and panic disorder
Leer MasEndocannabinoid System Components as Potential Biomarkers in Psychiatry
Leer MasNeuropsychophysiological Measures of Alcohol Dependence: Can We Use EEG in the Clinical Assessment?
Leer MasCannabidiol: A Potential New Alternative for the Treatment of Anxiety, Depression, and Psychotic Disorders
Leer MasCannabidiol does not display drug abuse potential in mice behavior
Leer MasGender differences in the effects of cannabidiol on ethanol binge drinking in mice
Leer MasMeasurement of CSF alpha-synuclein improves early differential diagnosis of mild cognitive impairment due to Alzheimer´s disease
Leer MasEffects of cannabidiol plus naltrexone on motivation and ethanol consumption
Leer MasCannabidiol regulates the expression of hypothalamus-pituitary-adrenal axis-related genes in response to acute restraint stress
Leer MasCannabidiol regulates behavioural alterations and gene expression changes induced by spontaneous cannabinoid withdrawal
Leer MasPharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol
Leer MasCannabinoid CB1 and CB2 receptors, and monoacylglycerol lipase gene expression alterations in the basal ganglia of patients with Parkinson’s disease
Leer MasAlterations in gene and protein expression of cannabinoid CB2 and GPR55 receptors in the dorsolateral prefrontal cortex of suicide victims
Leer MasDeletion of Dlk1 increases the vulnerability to developing anxiety-like behaviors and ethanol consumption in mice
Leer MasThe modulation of the startle reflex as predictor of alcohol use disorders in a sample of heavy drinkers: A 4-year follow-up study
Leer MasIs the cannabidiol potentially useful for the treatment of neuropsychiatric and drug-use disorders?
Leer MasThe rewarding effects of ethanol are modulated by binge eating of a high-fat diet during adolescence
Leer MasPsychological symptomatology and impaired prepulse inhibition of the startle reflex are associated with cannabis-induced psychosis
Leer MasDeletion of Dlk2 increases the vulnerability to anxiety-like behaviors and impairs the anxiolytic action of alprazolam
Leer MasInvolvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice
Leer MasDifferent molecular/behavioral endophenotypes in C57BL/6J mice predict the impact of OX1 receptor blockade on binge-like ethanol intake
Leer MasEffects of bingeing on fat during adolescence on the reinforcing effects of cocaine in adult male mice
Leer MasChanges in gene expression and sensitivity of cocaine reward produced by a continuous fat diet
Leer MasDisruption of blood-brain barrier integrity in postmortem alcoholic brain: preclinical evidence of TLR4 involvement from a binge-like drinking model
Leer MasInvolvement of the dynorphin/KOR system on the nociceptive, emotional and cognitive manifestations of joint pain in mice
Leer MasSocial defeat in adolescent mice increases vulnerability to alcohol consumption
Leer MasEffects of bingeing on fat during adolescence on the reinforcing effects of cocaine in adult male mice
Leer MasIncreased expression of readthrough acetylcholinesterase variants in the brains of Alzheimer's disease patients
Leer MasTopiramate increases the rewarding properties of cocaine in young-adult mice limiting its clinical usefulness
Leer MasEmily M. Johansson, María S. García-Gutiérrez, María Moscoso-Castro, Jorge Manzanares, Olga Valverde
Reduced Contextual Discrimination following Alcohol Consumption or MDMA Administration in Mice
Leer MasDifferential pharmacological regulation of sensorimotor gating deficit in CB1 knockout mice and associated neurochemical and histological alterations
Leer MasIncreased vulnerability to ethanol consumption in adolescent maternal separated mice
Leer MasEvidence against a critical role of CB1 receptors in adaptation of the hypothalamic-pituitary-adrenal axis and other consequences of daily repeated stress
Leer MasGestational and early postnatal hypothyroidism alters VGluT1 and VGAT bouton distribution in the neocortex and hippocampus, and behavior in rats
Leer MasAbnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims
Leer MasEffects of naltrexone plus topiramate on ethanol self-administration and tyrosine hydroxylase gene expression changes
Leer MasRegulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflammation in mice
Leer MasVoluntary alcohol drinking enhances proopiomelanocortin gene expression in nucleus accumbens shell and hypothalamus of Sardinian alcohol-preferring rats
Leer MasGene and protein alterations of FKBP5 and glucocorticoid receptor in the amygdala of suicide victims
Leer MasSynaptic plasticity alterations associated with memory impairment induced by deletion of CB2 cannabinoid receptors
Leer MasSpontaneous generation of infectious prion disease in transgenic mice
Leer MasRole of CB2 cannabinoid receptors in the rewarding, reinforcing, and physical effects of nicotine
Leer MasPregabalin- and topiramate-mediated regulation of cognitive and motor impulsivity in DBA/2 mice
Leer MasIncreased ethanol intake in prodynorphin knockout mice is associated to changes in opioid receptor function and dopamine transmission
Leer MasChanges in acetylcholinesterase expression are associated with altered presenilin-1 levels
Leer MasEndogenous cannabinoid system regulates intestinal barrier function in vivo through cannabinoid type 1 receptor activation
Leer MasChronic blockade of cannabinoid CB2 receptors induces anxiolytic-like actions associated with alterations in GABA(A) receptors
Leer MasOverexpression of CB2 cannabinoid receptors results in neuroprotection against behavioral and neurochemical alterations induced by intracaudate administration of 6-hydroxydopamine
Leer MasDecreased cocaine motor sensitization and self-administration in mice overexpressing cannabinoid CB₂ receptors
Leer MasInnate difference in the endocannabinoid signaling and its modulation by alcohol consumption in alcohol-preferring sP rats
Leer MasAccumbal dopamine, noradrenaline and serotonin activity after naloxone-conditioned place aversion in morphine-dependent mice
Leer MasOverexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice
Leer MasEndocannabinoid system and psychiatry: in search of a neurobiological basis for detrimental and potential therapeutic effects
Leer MasProdynorphin gene deletion increased anxiety-like behaviours, impaired the anxiolytic effect of bromazepam and altered GABAA receptor subunits gene expression in the amygdala
Leer MasDeletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice
Leer MasOverexpression of CB2 cannabinoid receptors decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice
Leer MasCannabinoid CB₂ receptor-mediated regulation of impulsive-like behaviour in DBA/2 mice
Leer MasPregabalin and topiramate regulate behavioural and brain gene transcription changes induced by spontaneous cannabinoid withdrawal in mice
Leer MasDecreased GABAA and GABAB receptor functional activity in cannabinoid CB1 receptor knockout mice
Leer MasRegulatory role of cannabinoid receptor 1 in stress-induced excitotoxicity and neuroinflammation
Leer MasIncreased vulnerability to 6-hydroxydopamine lesion and reduced development of dyskinesias in mice lacking CB1 cannabinoid receptors
Leer MasThe cannabinoid CB1 receptor is involved in the anxiolytic, sedative and amnesic actions of benzodiazepines
Leer MasDepression-resistant endophenotype in mice overexpressing cannabinoid CB(2) receptors
Leer MasCB1 receptor blockade decreases ethanol intake and associated neurochemical changes in fawn-hooded rats
Leer MasRegulation of Fas receptor/Fas-associated protein with death domain apoptotic complex and associated signalling systems by cannabinoid receptors in the mouse brain
Leer MasModulation of impulsivity by topiramate: implications for the treatment of alcohol dependence
Leer MasManipulation of fatty acid amide hydrolase functional activity alters sensitivity and dependence to ethanol
Leer MasInterferon-gamma is a critical modulator of CB(2) cannabinoid receptor signaling during neuropathic pain
Leer MasUse of cocaine by heavy drinkers increases vulnerability to developing alcohol dependence: a 4-year follow-up study
Leer MasTime dependent alterations on tyrosine hydroxylase, opioid and cannabinoid CB1 receptor gene expressions after acute ethanol administration in the rat brain
Leer MasCrucial role of CB(2) cannabinoid receptor in the regulation of central immune responses during neuropathic pain
Leer MasGene transcription alterations associated with decrease of ethanol intake induced by naltrexone in the brain of Wistar rats
Leer MasThe effects of topiramate adjunctive treatment added to antidepressants in patients with resistant obsessive-compulsive disorder
Leer MasRole of the cannabinoid system in pain control and therapeutic implications for the management of acute and chronic pain episodes
Leer MasTime course of opioid and cannabinoid gene transcription alterations induced by repeated administration with fluoxetine in the rat brain
Leer MasKappa- and delta-opioid receptor functional activities are increased in the caudate putamen of cannabinoid CB1 receptor knockout mice
Leer MasEffects of repeated administration with CP-55,940, a cannabinoid CB1 receptor agonist on the metabolism of the hepatic heme
Leer MasChronic ethanol consumption regulates cannabinoid CB1 receptor gene expression in selected regions of rat brain
Leer MasCannabinoid-opioid crosstalk in the central nervous system
Leer MasTopiramate in the treatment of alcohol dependence: A Case Series
Leer MasImpaired action of anxiolytics in mice deficient in cannabinoid CB1 receptors
Leer MasRepeated administration of 9-tetrahydrocannabinol produces a differential time-related regulation of µ-opioid receptors in the rat brain
Leer MasRole of the neuronal cannabinoid system in mental diseases.
Leer MasDifferences in basal cannabinoid CB1 receptor function in selective brain areas and vulnerability to alcohol consumption between Wistar and Fawn Hooded rats
Leer MasSpontaneous cannabinoid withdrawal produces differential time-related alterations in cannabinoid CB1 receptor gene expression in the mouse brain
Leer MasExtinction of cocaine self-administration produces alterations in corticotropin releasing factor gene expression in the paraventricular nucleus of the hypothalamus
Leer MasDesign and Synthesis of S -()-2-[[4-(napht-1-yl)piperazin-1-yl ] methyl ]-1,4-dioxoperhydropyrrolo [1,2-a ]pyrazine (CSP-2503) Using Computational Simulation. A 5-HT1A Receptor Agonist
Leer MasBehavioral and gene transcription alterations induced by spontaneous cannabinoid withdrawal in mice.
Leer MasNaltrexone for alcohol dependence
Leer MasSexual differences in the chronic treatment with 9-tetrahydrocannabinol on proenkephalin gene expression in the hypothalamus of the rat.
Leer MasLoss of cannabinoid CB1 receptors and alleviation of motor hyperactivity and neurochemical deficits by endocannabinoid uptake inhibition in a rat model of Huntington´s disease
Leer MasNaltrexone improves outcome of a controlled drinking program
Leer MasCerebrospinal fluid and plasma nitrate levels are increased in patients with Lewy body disease
Leer MasGastrin-releasing peptide mediated regulation of 5-HT neuronal activity in the hypothalamic paraventricular nucleus under basal and restraint stress
Leer MasSerum levels of Coenzyme Q in patients with Lewy body disease
Leer MasSex-dependent changes in prodynorphin and proopiomelanocortin gene expression in several brain regions of rats fetuses prenatally exposed to 9-tetrahydrocannabinol
Leer MasRole of gonadal steroids in corticotropin releasing factor and proopiomelanocortin gene expression response to 9-tetrahydrocannabinol in the hypothalamus of the rat
Leer MasExtinction of cocaine self-administration produces a differential time-related regulation of proenkephalin gene expression in rat brain
Leer MasAnandamide, but not 2-arachidonylglycerol, accumulates during in vivo neurodegeneration
Leer MasSynthesis and structure-activity relationships of a new model of aylpiperazines. 5.1 Study of the physicochemical influence of the pharmacophore on 5-HT1A/1-adrenergic receptor affinity: synthesis of a new derivative with mixed 5-HT1A/D2 antagonist properties
Leer MasBiochemical, electrophysiological and neurohormonal studies with B-20991, a selective 5-HT1A receptor agonist
Leer MasSex steroid influence on cannabinoid CB1 receptor mRNA and endocannabinoid levels in the anterior pituitary gland
Leer MasUnilateral 6-hydroxydopamine lesions of the nigrostriatal dopaminergic neurons increased cannabinoid CB1 receptor mRNA levels in striatal efferent neurons: relationship with changes in mRNA levels of tyrosine hydroxylase, proenkephalin, substance P and glutamic acid decarboxylase
Leer MasPrenatal 9-tetrahydrocannabinol exposure modifies proenkephalin gene expression in the fetal rat brain: sex-dependent differences
Leer MasTime dependent differences of repeated administration with 9-tetrahydrocannabinol in proenkephalin and cannabinoid receptor gene expression and G-protein activation by µ-opioid and cannabinoid receptors in the caudate-putamen
Leer MasIdentification of endocannabinoids and cannabinoid CB1 receptor mRNA in the pituitary gland
Leer MasHypothalamus, anterior pituitary and adrenal gland involvement in the activation of ACTH and corticosterone by gastrin-releasing peptide
Leer MasChronic treatment with the cannabinoid receptor agonist CP-55,940 regulates corticotropin releasing factor and proopiomelanocortin gene expression in the hypothalamus and pituitary gland of the rat
Leer MasRepeated administration of 9-tetrahydrocannabinol produces a differential time related responsiveness on proenkephalin, proopiomelanocortin and corticotropin releasing factor gene expression in the hypothalamus and pituitary gland of the rat
Leer MasDifferential basal proenkephalin gene expression in dorsal striatum and nucleus accumbens, and vulnerability to morphine self-administration in Fischer 344 and Lewis rats
Leer MasDesign and synthesis of 2-[4-[4(m-Ethylsulfonamido)-phenyl)piperazin-1-yl]butyl]-1,3-dioxoperhydropyrrolo[1,2-c]imidazole (EF-7412) using neural networks: A selective derivative with mixed 5-HT1A/D2 antagonist properties
Leer MasOpioid and cannabinoid mediated regulation of the increase in ACTH and corticosterone plasma concentrations induced by central administration of 9-tetrahydrocannabinol
Leer MasPharmacological and biochemical interactions between opiates and cannabinoids
Leer MasPreclinical pharmacology of B-20991, a 5-HT1A receptor agonist with anxiolytic activity
Leer MasRU-486 blocks stress-induced enhancement of proenkephalin gene expression in the paraventricular nucleus of rat hypothalamus
Leer MasTime-course of the cannabinoid receptor down-regulation in the adult brain caused by repeated exposure to 9-tetrahydrocannabinol
Leer MasAcute and repeated ECS treatment increases CRF, POMC and PENK gene expression in selected regions of the rat hypothalamus
Leer MasChronic administration of cannabinoids regulates proenkephalin mRNA levels in selected regions of the rat brain
Leer MasRole of CRF in gastrin releasing peptide (GRP)-mediated regulation of ACTH and corticosterone secretion in male rats
Leer MasPerinatal 9-tetrahydrocannabinol exposure in rats reduces proenkephalin gene expression in the caudate-putamen of adult females but not of adult males
Leer Mas9-tetrahydrocannabinol increases prodynorphin and preproenkephalin gene expression in the spinal cord of the rat
Leer MasDifferential 5HT-mediated regulation of stress-induced activation of proopiomelanocortin (POMC) gene expression in the anterior and intermediate lobe of the pituitary in male rats
Leer Mas9-tetrahydrocannabinol increases proopiomelanocortin gene expression in the arcuate nucleus of the rat hypothalamus
Leer MasSynthesis and structure-activity relationships of a new model of arylpiperazines. 1. 2-[4-(o-methoxyphenyl)piperazin-1-ylmethyl]-1,3-dioxo-perhydroimidazo[1,5-a]pyridine: A selective 5HT1A receptor agonist
Leer MasNeurochemical evidence that estrogen-induced suppression of kappa opioid receptor-mediated regulation of tuberoinfundibular dopaminergic neurons is prolactin independent
Leer MasGender differences in tuberoinfundibular dopaminergic neuronal activity in a photoperiodic rodent (Mesocricetus auratus)
Leer MasMDL-101,562 blocks the stimulatory effects of bombesin and GRP on hypothalamic dopaminergic neurons
Leer MasThe effects of short-photoperiod exposure on tuberoinfundibular dopamine neurons in male and female Syrian hamster
Leer MasDelta opioid receptor-mediated regulation of central dopaminergic neurons
Leer MasKappa opioid mediated regulation of prolactin and -melanocyte-stimulating hormone in male and female rats
Leer Mas5HT2 Receptors mediate the effects of stress on the activity of periventricular hypophysial dopaminergic neurons and the secretion of -melanocyte-stimulating hormone
Leer MasPlasmatic somatostatin as a marker of positive symptoms of schizophrenia
Leer MasSexual differences in the stimulatory effects of bombesin on tuberoinfundibular dopaminergic neurons
Leer MasCharacterization of opioid receptor mediated regulation of incertohypothalamic dopamine neurons: lack of evidence for a role of 5-hydroxytryptaminergic neurons in mediating the stimulatory effects of morphine
Leer MasSexual differences in the activity of periventricular-tuberohypophysial dopamine neurons in rats
Leer MasSexual differences in kappa opioid receptor-mediated regulation of tuberoinfundibular dopaminergic neurons
Leer MasEffects of immunoneutralization of dynorphin1-17 and dynorphin1-8 on the activity of central dopaminergic neurons in the male rat
Leer MasNoradrenergic innervation to the VMN or MPN is not necessary for lordosis
Leer MasKappa opioid receptor-mediated regulation of dopaminergic neurons in the rat brain
Leer MasActivation of tuberohypophysial dopamine neurons following intracerebroventricular administration of the selective kappa antagonist nor-binaltorphimine
Leer Mas3-Methoxy-4-hydroxyphenylethyleneglycol concentrations in discrete hypothalamic nuclei reflect the activity of noradrenergic neurons
Leer MasActivation of tuberoinfundibular and tuberohypophysial dopaminergic neurons following intracerebroventricular administration of bombesin
Leer MasAtrial natriuretic peptide (ANP)-induced suppression of vasopressin secretion is not mediated by hypothalamic dopamine neurons
Leer MasThe role of kappa opioid receptor-mediated mechanisms in the regulation of tuberohypophysial dopaminergic neurons and the secretion of -melanocyte stimulating hormone
Leer MasAmphetamine and chlorpromazine modify brain insulin levels in the rat
Leer MasLevels of insulin in the brains of rats modified by chronic administration of amphetamine, haloperidol and sulpiride
Leer MasAmphetamine and chlorpromazine modify brain insulin levels in the rat
Leer MasEffect of beta-pyridil-carbinol on platelet aggregation
Leer MasIn vitro and in vivo antiaggregant effects of magnesium halogenates
Leer MasRecherches préliminaires sur le Carthamus Lanatus
Leer Mas